A cluster of Chlamydia serpentis cases in captive snakes

Vet Microbiol. 2020 Jan:240:108499. doi: 10.1016/j.vetmic.2019.108499. Epub 2019 Nov 14.

Abstract

Following the occurrence of sudden death cases in a zoo reptile collection, histological analyses conducted on tissues from two common adders suggested an infection due to Chlamydia. The survey was extended to 22 individual snakes from the same collection and a PCR analysis targeting a conserved gene in Chlamydiaceae revealed bacterial shedding in six of them. The infection resolved spontaneously in one snake whereas another one succumbed one month later. The antibiotic treatment administered (marbofloxacin) to the remaining four PCR positive animals stopped the mortalities and the shedding. Analysis of the 16S and 23S ribosomal gene sequences identified C. serpentis, a recently described novel chlamydial species in snakes. A PCR tool for a quick and specific identification of this new chlamydial species was developed in this study.

Keywords: Chlamydia serpentis; PCR; Treatment.

MeSH terms

  • Animals
  • Animals, Zoo / microbiology
  • Anti-Bacterial Agents / therapeutic use*
  • Chlamydia / classification*
  • Chlamydia / drug effects*
  • Chlamydia Infections / drug therapy
  • Chlamydia Infections / veterinary*
  • Feces / microbiology
  • Female
  • Fluoroquinolones / therapeutic use*
  • Male
  • Phylogeny
  • Snakes / microbiology*

Substances

  • Anti-Bacterial Agents
  • Fluoroquinolones
  • marbofloxacin